![]() ![]() The majority of averted deaths, 67,300 per year, would occur in those age ≥75 years because of the high event rate in this group ( 4).Īs with any treatment, aggressive antihypertensive therapy may affect individual subjects of clinical trials in different ways as a function of their baseline characteristics, a phenomenon called heterogeneity of treatment effect (HTE). By applying stricter goals in adults at high risk for or with cardiovascular (CV) disease, it is estimated that 107,500 deaths could be averted annually in the United States. ![]() Since 2017, largely as a result of findings from SPRINT (Systolic Pressure Intervention Trial), the American College of Cardiology/American Heart Association and the European Society of Cardiology/European Society of Hypertension have advocated intensive blood pressure control ( 1–3).
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